| Cat. No. |
Product Name |
Information |
| PC-25277 |
PTC-003
MAPT splicing modulator
|
PTC-003 is a potent splicing modulator compound (SMC) that correct microtubule-associated protein tau (MAPT) splicing with EC2x value of 5.2 nM in MAPT minigene assay in HEK293T cells (3R MAPT), promotes MAPT exon 10 exclusion, increasing 3R MAPT transcript and protein levels. |
| PC-25275 |
Cycloleucine
MAT2A inhibitor
|
Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation, is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro, also inhibits MAT2A, Cycloleucine is an antagonist of NMDA receptor associated glycine receptor. |
| PC-25274 |
AGI-24512
MAT2A inhibitor
|
AGI-24512 is a highly potent, cell-active methionine adenosyltransferase 2α (MAT2A) inhibitor with enzymatic IC50 of 8 nM. |
| PC-25267 |
Ac5GlutolNAc
RENBP inhibitor
|
Ac5GlutolNAc is a specific small molecule inhibitor of GlcNAc 2-epimerase (RENBP), selectively enhances the labeling efficiency of tetraacetyl-N-azidoacetylmannosamine (AAM) in antigen-presenting cells (APCs), but not non-APCs. |
| PC-25223 |
AGPAT4 inhibitor CL26
AGPAT4 inhibitor
|
AGPAT4 inhibitor CL26 is a potent, isoform-specific, covalent inhibitor of acylglycerol-3-phosphate o-acyltransferase 4 (AGPAT4) inhibitor with IC50 of 795 nM, binds to Cys228 of AGPAT4. |
| PC-25222 |
ASS1 inhibitor C-01
ASS1 inhibitor
|
ASS1 inhibitor C-01 is a small molecule inhibitor of argininosuccinate synthetase 1 (ASS1), binds to ASS1 directly with SPR Kd of 18.8 nM. |
| PC-25219 |
Chlorogenic acid
G6PT1 inhibitor
|
Chlorogenic acid (3-O-Caffeoylquinic acid, Heriguard, NSC 407296) is a major phenolic compound in Lonicera japonica Thunb, is an orally active with antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension activities, is a competitive inhibitor of glucose 6-phosphate transporter (G6PT1). |
| PC-25207 |
YB-B1
YBX1 inhibitor
|
YB-B1 is a small molecule Y-box-binding protein 1 (YBX1, YB-1) inhibitor, directly binds to YBX1 protein with SPR KD value of 5.67 uM. |
| PC-25184 |
JX-078
LAT1 inhibitor
|
JX-078 is a potent, selective inhibitor of L-type amino acid transporters LAT1 (SLC7A5), inhibits [3H]-L-leucine uptake into HT-29 cells with IC50 of 121 nM, >10-fold selective over in LAT2. |
| PC-25173 |
Pyrabactin
ABA receptor agonist
|
Pyrabactin is a specific, synthetic abscisic acid (ABA) agonist that selectively inhibits seed germination, promotes interactions between HAB1 and PYR1, PYL1 or PYL3. |
| PC-25171 |
Cyanabactin
ABA receptor agonist
|
Cyanabactin is a potent and selective plant hormone abscisic acid (ABA) receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency, exhihibits a wide spectrum of ABA-like activities. |
| PC-25170 |
ABA receptor agonist iCB
ABA receptor agonist
|
ABA receptor agonist iCB is a novel synthetic abscisic acid (ABA) receptor agonist with broad-spectrum activation across the three receptor subtypes, has IC50 of 0.16 uM in seedling establishment inhibition assay. |
