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首页-小分子抑制剂&激动剂-Others-Other Targets-AF38469
AF38469

Chemical Structure : AF38469

CAS No.: 1531634-31-7

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AF38469 (AF-38469)

货号: PC-43219Not For Human Use, Lab Use Only.

AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.

规格 价格 库存 数量
10 mg ￥1980 In stock
25 mg ￥3280 In stock
100 mg ￥7980 In stock
200 mg Get quote
1 g Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
AF38469 shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin ETA/B, MMP-12).

物理化学性质&存储条件

分子量 324.2546
分子式 C15H11F3N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 43 mg/mL
Chemical Name/SMILES

Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)-

参考文献

1. Schrøder TJ, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.

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