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首页-小分子抑制剂&激动剂-Others-Other Targets-STL427944
STL427944

Chemical Structure : STL427944

CAS No.: 292028-62-7

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STL427944 (STL 427944)

货号: PC-22338Not For Human Use, Lab Use Only.

STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

物理化学性质&存储条件

分子量 485.50
分子式 C25H23N7O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-((2-(4-morpholino-6-(phenylamino)-1,3,5-triazin-2-yl)hydrazineylidene)methyl)phenyl furan-2-carboxylate

参考文献

1. Chesnokov MS, et al. Cell Death Dis. 2021 Jul 14;12(7):704.

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