YKJ-124 | Aster-A inhibitor | Probechem Biochemicals

Chemical Structure : YKJ-124

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YKJ-124 (YKJ124)

货号: PC-27981Not For Human Use, Lab Use Only.

YKJ-124 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-A without affecting other cholesterol transport pathways, attenuates the suppression of nuclear SREBP2 by cyclodextrin-cholesterol in CHO cells, increases plasma membrane accessible cholesterol and potentiates store-operated Ca2+ entry in Th17 cells.

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生物&药学活性

YKJ-124 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-A without affecting other cholesterol transport pathways, attenuates the suppression of nuclear SREBP2 by cyclodextrin-cholesterol in CHO cells, increases plasma membrane accessible cholesterol and potentiates store-operated Ca2+ entry in Th17 cells.

物理化学性质&存储条件

分子量	322.36
分子式	C19H18N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(6-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)quinolin-2-yl)propan-2-ol

参考文献

1. Hyunsoo Kim, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2617638123.

YKJ-124 (YKJ124)

生物&药学活性

物理化学性质&存储条件

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YKJ-124 (YKJ124)

生物&药学活性

物理化学性质&存储条件

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