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首页-小分子抑制剂&激动剂-Others-Other Targets-BDP-13176
BDP-13176

Chemical Structure : BDP-13176

CAS No.: 2290660-61-4

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BDP-13176 (BDP 13176, BDP13176)

货号: PC-21071Not For Human Use, Lab Use Only.

BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.

规格 价格 库存 数量
5 mg ￥2280 In stock
10 mg ￥3880 In stock
25 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.
BDP-13176 is a useful chemical probe for fascin's potential role in tumor invasion and metastasis.

物理化学性质&存储条件

分子量 497.38
分子式 C24H22Cl2N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl-

参考文献

1. Stuart Francis, et al. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1023-1029.

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