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首页-小分子抑制剂&激动剂-Others-Other Targets-EG1
EG1

Chemical Structure : EG1

CAS No.: 693241-54-2

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EG1 (Pax2 inhibitor EG1)

货号: PC-62416Not For Human Use, Lab Use Only.

Pax2 inhibitor EG1 (EG1) is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
50 mg ￥5280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pax2 inhibitor EG1 (EG1) is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM.
EG1 inhibits Pax2 mediated expression with IC50 of 10 uM, and inhibits proliferation of Pax2 positive renal and ovarian cancer cell lines but has little effect on Pax2 negative cancer cells.
EG1 inhibits embryonic kidney development.

物理化学性质&存储条件

分子量 390.395
分子式 C22H18N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-(2-methoxybenzamido)benzamido)benzoic acid

参考文献

1. Grimley E, et al. ACS Chem Biol. 2017 Mar 17;12(3):724-734.

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