ZG111

Chemical Structure : ZG111

加入收藏

货号: PC-23497Not For Human Use, Lab Use Only.

ZG111 is a potent ClpP agonist with EC50 of 1.19 uM, binds to ClpP and promotes the ClpP-mediated degradation of respiratory chain complexes.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ZG111 is a potent ClpP agonist with EC50 of 1.19 uM, binds to ClpP and promotes the ClpP-mediated degradation of respiratory chain complexes.
ZG111 exerts an antiproliferation effect on PDAC cells via aberrant ClpP activation in mitochondria.
ZG111 activates the JNK/c-Jun pathway and triggers an ER stress response in a ClpP-dependent manner.
ZG111 exerts antitumor effects in PDAC mice models with different KRAS genetic types.

物理化学性质&存储条件

分子量	577.52
分子式	C30H33BrN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(6S,9aS)-N-(4-bromobenzyl)-6-((S)-sec-butyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

参考文献

1. Wang P, et al. Cell Chem Biol. 2022 Sep 15;29(9):1396-1408.e8.

ZG111

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ZG111

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.