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Warfarin

Chemical Structure : Warfarin

CAS No.: 81-81-2

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Warfarin (WARF-42, Athrombine-K)

货号: PC-23520Not For Human Use, Lab Use Only.

Warfarin (WARF-42, Athrombine-K) is a potent anticoagulant agent and a vitamin K1 recycling antagonist to deplete active vitamin K1, is a small molecular inhibitor of vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1).

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1 g ￥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Warfarin (WARF-42, Athrombine-K) is a potent anticoagulant agent and a vitamin K1 recycling antagonist to deplete active vitamin K1, is a small molecular inhibitor of vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1).
Warfarin promotes ferroptosis, represses tumor growth by promoting ferroptosis in both immunodeficient and immunocompetent mouse models.
Warfarin is a potential repurposing drug in cancer therapy, particularly for tumors with high levels of VKORC1L1 expression.

物理化学性质&存储条件

分子量 308.33
分子式 C19H16O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-

参考文献

1. Yang X, et al. Cell Metab. 2023 Aug 8;35(8):1474-1490.e8.

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