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首页-小分子抑制剂&激动剂-Others-Other Targets-Malabaricone C
Malabaricone C

Chemical Structure : Malabaricone C

CAS No.: 63335-25-1

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Malabaricone C

货号: PC-23282Not For Human Use, Lab Use Only.

Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Malabaricone C is a natural sphingomyelin synthases (SMSs) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively. effectively suppresses male ESCC cell proliferation and xenograft tumor growth

物理化学性质&存储条件

分子量 358.43
分子式 C21H26O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one

参考文献

1. Othman MA, et al. ACS Med Chem Lett. 2019;10(8):1154-1158.

2. Gong T, et al. Oncogene. 2024 Oct 23. doi: 10.1038/s41388-024-03193-z.

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