Them1 inhibitor Compound U11

Chemical Structure : Them1 inhibitor Compound U11

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货号: PC-25886Not For Human Use, Lab Use Only.

Them1 inhibitor Compound U11 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 3.63 uM, selectively inhibits Them1 by binding the START domain (Kd=0.67 uM).

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250 mg		Get quote

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Them1 inhibitor Compound U11 is a small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 3.63 uM, selectively inhibits Them1 by binding the START domain (Kd=0.67 uM).

物理化学性质&存储条件

分子量	381.54
分子式	C22H27N3OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methyl-1-(4-((2-methyl-1H-indol-3-yl)(thiophen-2-yl)methyl)piperazin-1-yl)propan-1-one

参考文献

1. Krumm CS, et al. Mol Metab. 2023 Dec;78:101832.