3-Nitrooxypropanol | MCR inhibitor | Probechem Biochemicals

Chemical Structure : 3-Nitrooxypropanol

CAS No.: 100502-66-7

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3-Nitrooxypropanol (3-NOP)

货号: PC-25841Not For Human Use, Lab Use Only.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg	￥3280	In stock
250 mg		Get quote

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生物&药学活性

3-Nitrooxypropanol (Abrucomstat, 3-NOP) is a small molecule inhibitor of methane formation in the rumen, specifically inhibits methyl-coenzyme M reductase (MCR), inhibit methanogenesis, in vitro and in vivo.
3-Nitrooxypropanol (3-NOP) persistently decreases enteric methane emissions from sheep, dairy cows, and beef cattle without apparent negative side effects.
3-Nitrooxypropanol (3-NOP) increass body weight gain significantly without negatively affecting feed intake nor milk production and composition.
3-Nitrooxypropanol (3-NOP) inhibits growth of two methanogenic archaea on H2 (80%) and CO2 (20%).
3-Nitrooxypropanol (3-NOP) is highly specific toward methanogenic archaea.

物理化学性质&存储条件

分子量	121.09
分子式	C3H7NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Hydroxypropyl nitrate

参考文献

1. Duin EC, et al. Proc Natl Acad Sci U S A. 2016 May 31;113(22):6172-7.

2. Liu Z, et al. Appl Environ Microbiol. 2022 Mar 22;88(6):e0190821.

3. Pitta DW, et al. Microbiome. 2022 Sep 13;10(1):146.

3-Nitrooxypropanol (3-NOP)

生物&药学活性

物理化学性质&存储条件

参考文献

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3-Nitrooxypropanol (3-NOP)

生物&药学活性

物理化学性质&存储条件

参考文献

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