欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Others-Other Targets-Epeleuton
Epeleuton

Chemical Structure : Epeleuton

CAS No.: 1667760-39-5

加入收藏

Epeleuton (15 hydroxy eicosapentaenoic acid ethyl ester)

货号: PC-61376Not For Human Use, Lab Use Only.

Epeleuton is an orally administered, second-generation ω-3 fatty acid derivative of C20:5 n-3 EPA, protects against cellular stress associated with SCD and supports early initiation of the resolution phase of inflammation.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Epeleuton is an orally administered, second-generation ω-3 fatty acid derivative of C20:5 n-3 EPA, protects against cellular stress associated with SCD and supports early initiation of the resolution phase of inflammation.
    Epeleuton has protective effects against inflammatory vasculopathy and markers of systemic inflammation, suggesting its possible transferability to SCD.
    Epeleuton significantly increased organ concentrations of 15-HEPE, which has both anti-inflammatory and pro-resolving functions.
    Epeleuton reduces circulating neutrophils and promotes a pro-resolving lipidomic profile in lung and liver of mice with sickle cell disease.
    Epeleuton promotes a pro-resolving profile in target organs and prevents the activation of the NF-kB pathway in mice with sickle cell disease.

    物理化学性质&存储条件

    分子量 346.511
    分子式 C22H34O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Ethyl (5Z,8Z,11Z,13E,15S,17Z)-15-hydroxyicosa-5,8,11,13,17-pentaenoate

    参考文献

    1. Mattè A, et al. Haematologica. 2024 Jun 1;109(6):1918-1932.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: