Peptide SBT-20 | ROS-lowering peptide | Probechem Biochemicals

Chemical Structure : Peptide SBT-20

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Peptide SBT-20 (SS-20, Phe-D-Arg-Phe-Lys-NH2)

货号: PC-22980Not For Human Use, Lab Use Only.

Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation.

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生物&药学活性

Peptide SBT-20 (SS-20) is a cell-permeable peptide targeting the inner mitochondrial membrane, reduces ROS, normalizes electron transport chain function and ATP generation.
SBT-20 significantly reduced infarct size in two different models of myocardial injury, but did not affect hemodynamics or no-reflow area in rat heart.
SBT-20 alleviated the inflammation and oxidation in HK-2 injury via controlling the mitochondrial function.
SBT-20 prevented apoptosis and inflammation and recovered the renal function through restoring mitochondrial function in vivo.

物理化学性质&存储条件

分子量	595.75
分子式	C30H45N9O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sequence: Phe-D-Arg-Phe-Lys-NH2

参考文献

1. Dai W, et al. Cardiovasc Drugs Ther. 2016 Dec;30(6):559-566.

2. Sun L, et al. Aging (Albany NY). 2020 Sep 25;12(18):18238-18250.

Peptide SBT-20 (SS-20, Phe-D-Arg-Phe-Lys-NH2)

生物&药学活性

物理化学性质&存储条件

参考文献

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Peptide SBT-20 (SS-20, Phe-D-Arg-Phe-Lys-NH2)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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询单

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