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首页-小分子抑制剂&激动剂-Others-Other Targets-CDD-3290
CDD-3290

Chemical Structure : CDD-3290

CAS No.:

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CDD-3290 (CDD3290)

货号: PC-23067Not For Human Use, Lab Use Only.

CDD-3290 is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CDD-3290 is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.
CDD-3290 shows minimal inhibitory activity against elastase (Ki = 1.18 mM) and is 12.7-fold less potent against α-chymotrypsin (Ki = 2.74 μM).
CDD-3290l exhibits similar inhibition against thrombin (Ki = 0.411 μM).

物理化学性质&存储条件

分子量 334.34
分子式 C17H14N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(5-amino-3-(6-methoxypyridin-3-yl)-1H-pyrazol-1-yl)(1H-benzo[d]imidazol-5-yl)methanone

参考文献

1. Erickson JA, et al. ACS Med Chem Lett. 2024 Aug 5;15(9):1526-1532.

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