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R-283

Chemical Structure : R-283

CAS No.: 135273-74-4

R-283 (R283)

货号: PC-61734Not For Human Use, Lab Use Only.

R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM.

物理化学性质&存储条件

分子量 220.715
分子式 C8H13ClN2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,3-dimethyl-2-((2-oxopropyl)thio)-1H-imidazol-3-ium chloride

参考文献

1. Griffin M, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5559-62.

2. Freund KF, et al. Biochemistry. 1994 Aug 23;33(33):10109-19.

3. Miura A, et al. J Biol Chem. 2013 Nov 8;288(45):32720-30.

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