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首页-小分子抑制剂&激动剂-Others-Other Targets-BAMB-4
BAMB-4

Chemical Structure : BAMB-4

CAS No.: 891025-25-5

BAMB-4 (ITPKA-IN-C14)

货号: PC-45040Not For Human Use, Lab Use Only.

BAMB-4 is a specific and membrane-permeable inhibitor of the InsP3Kinase activity of ITPKA (inositol-1,4,5-trisphosphate-3-kinase A) with IC50 of 20 uM.

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5 mg ¥1380 In stock
10 mg ¥2280 In stock
25 mg ¥3880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BAMB-4 is a specific and membrane-permeable inhibitor of the InsP3Kinase activity of ITPKA (inositol-1,4,5-trisphosphate-3-kinase A) with IC50 of 20 uM.
BAMB-4 shows an inhibitory effect only in one from 42 targets tested.
BAMB-4 is a promising therapeutic approach in lung cancer therapy.

物理化学性质&存储条件

分子量 252.268
分子式 C15H12N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

Benzamide, N-1,2-benzisoxazol-3-yl-4-methyl-

参考文献

1. Schröder D, et al. Biochem Biophys Res Commun. 2013 Sep 20;439(2):228-34.

2. Schröder D, et al. Biochem Pharmacol. 2015 Jul 15;96(2):143-50.

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