DZ2002 | SAHH inhibitor | Probechem Biochemicals

Chemical Structure : DZ2002

CAS No.: 33231-14-0

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DZ2002 (DZ-2002)

货号: PC-45486Not For Human Use, Lab Use Only.

DZ2002 is a potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM.

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5 mg	￥2380	In stock
10 mg	￥3880	In stock
25 mg	￥5980	In stock
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生物&药学活性

DZ2002 is a potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM.
DZ2002 is more effectively than type I inhibitor DHCaA with greatly reduced cytotoxicity.
DZ2002 significantly reduces both a mixed lymphocyte reaction and IL-12 production from in vitro-stimulated splenocytes.
DZ2002 suppresses a delayed-type hypersensitivity reaction and antibody secretion in vivo.

物理化学性质&存储条件

分子量	251.2419
分子式	C10H13N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 61 mg/mL
Chemical Name/SMILES	9H-Purine-9-butanoic acid, 6-amino-α-hydroxy-, methyl ester

参考文献

1. Wu QL, et al. J Pharmacol Exp Ther. 2005 May;313(2):705-11.

2. Fu YF, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1229-37.

3. Kominsky DJ, et al. J Immunol. 2011 Jun 1;186(11):6505-14.

DZ2002 (DZ-2002)

生物&药学活性

物理化学性质&存储条件

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DZ2002 (DZ-2002)

生物&药学活性

物理化学性质&存储条件

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