Conduritol B epoxide | β-glucosidase inhibitor | Probechem Biochemicals

Chemical Structure : Conduritol B epoxide

CAS No.: 6090-95-5

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Conduritol B epoxide (CBE)

货号: PC-42291Not For Human Use, Lab Use Only.

Conduritol B epoxide is a potent, specific, irreversible glucocerebrosidase (acid β-glucosidase) inhibitor with Ki of 53 uM.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg	￥2980	In stock
250 mg		Get quote

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生物&药学活性

Conduritol B epoxide is a potent, specific, irreversible glucocerebrosidase (β-glucosidase) inhibitor with Ki of 53 uM.
Conduritol B epoxide does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase.
Conduritol B epoxide is a useful tool to study Gaucher disease.

物理化学性质&存储条件

分子量	162.1406
分子式	C6H10O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: ≥ 22 mg/mL
Chemical Name/SMILES	myo-Inositol, 1,2-anhydro-

参考文献

1. Ogawa S, et al. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1493-8.

2. Witte MD, et al. Nat Chem Biol. 2010 Dec;6(12):907-13.

3. Newburg DS, et al. Biochim Biophys Acta. 1986 Jun 11;877(1):121-6.

4. Liou B, et al. Hum Mol Genet. 2016 Dec 1;25(23):5126-5141.

Conduritol B epoxide (CBE)

生物&药学活性

物理化学性质&存储条件

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Conduritol B epoxide (CBE)

生物&药学活性

物理化学性质&存储条件

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