RR6 | Vanin inhibitor | Probechem Biochemicals

Chemical Structure : RR6

CAS No.: 1351758-37-6

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RR6 (Vanin inhibitor RR6)

货号: PC-45557Not For Human Use, Lab Use Only.

RR6 is a selective, reversible, and competitive Vanin inhibitor with IC50 of 0.54 uM for hVVN1 pantetheinase (vanin-1).

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5 mg	￥1780	In stock
10 mg	￥2780	In stock
25 mg	￥4880	In stock
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100 mg		Get quote

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生物&药学活性

RR6 is a selective, reversible, and competitive Vanin inhibitor with IC50 of 0.54 uM for hVVN1 pantetheinase (vanin-1).
RR6 completely inhibits plasma vanin activity and caused alterations of plasma lipid concentrations in rats.
RR6 inhibits PDGF-induced SMC proliferation and protects SMCs from TNF-α-induced apoptosis in vitro, attenuates transplant vasculopathy in rat aortic allografts; orally bioactive.

物理化学性质&存储条件

分子量	293.3581
分子式	C16H23NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanamide, 2-hydroxy-3-(hydroxymethyl)-3-methyl-N-(3-oxo-4-phenylbutyl)-, (2R)-

参考文献

1. Jansen PA, et al. ACS Chem Biol. 2013 Mar 15;8(3):530-4.

2. van Diepen JA, et al. Sci Rep. 2016 Mar 2;6:21906.

3. Wedel J, et al. Transplantation. 2016 Aug;100(8):1656-66.

RR6 (Vanin inhibitor RR6)

生物&药学活性

物理化学性质&存储条件

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RR6 (Vanin inhibitor RR6)

生物&药学活性

物理化学性质&存储条件

参考文献

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