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Amcasertib

Chemical Structure : Amcasertib

CAS No.: 1129403-56-0

Amcasertib (BBI-503, BBI503)

货号: PC-45384Not For Human Use, Lab Use Only.

Amcasertib (BBI503) is a small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amcasertib (BBI503) is a small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases.
Amcasertib targets and inhibits one or more pathways involved in cancer stem cell survival, shows potential antineoplastic activity.

物理化学性质&存储条件

分子量 539.691
分子式 C31H33N5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-

参考文献

1. Marcucci F, et al. Front Oncol. 2016 May 10;6:115.

2. Iv Santaliz-Ruiz LE, et al. Int J Cancer. 2014 Dec 15;135(12):2741-8.

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