| Cat. No. |
Product Name |
Information |
| PC-28065 |
Rusfertide
Hepcidin mimetic, Ferroportin inhibitor
|
Rusfertide (PTG-300) is a peptidic mimetic of hepcidin that binds to ferroportin and decreases iron delivery to bone marrow, reducing the production of red blood cells, shows potential for polycythemia vera and hemochromatosis. |
| PC-28038 |
NSC678917
BAIAP2 inhibitor
|
NSC678917 is a small molecule inhibitor of BAR/IMD domain-containing adaptor protein 2 (BAIAP2, IRSp53) binds to cytoskeletal scaffolding protein BAIAP2 and inhibits MB cell proliferation and migration. |
| PC-28037 |
C273 trihydrochloride
Mitochondrial complex I modulator
|
C273 trihydrochloride is a potent, selective, oral bioavailable, and brain penetratn mitochondrial complex I (mtCI; NADH:ubiquinone oxidoreductase) modulator, protects against Aβ toxicity via modulation of mtCI. |
| PC-28036 |
BDA-41
CBX7 inhibitor
|
BDA-41 is an allosteric P. falciparum aspartate transcarbamoylase (PfATC) inhibitor, also is a polycomb group protein chromobox 7 (CBX7) inhibitor. |
| PC-28035 |
EC134
CBX7 inhibitor
|
EC134 is a potent, cell-active small-molecule inhibitor of CBX7 with IC50 of 34 uM in FP assays, inhibits viability of OCI-AML3 with IC50 of 22 uM. |
| PC-27990 |
SI409-1
DLST K409 succinylation inhibitor
|
SI409-1 is a specific small molecule inhibitor of dihydrolipoamide S-succinyltransferase (DLST) lysine 409 (K409), effectively inhibits DLST K409 succinylation (K409succ). |
| PC-27984 |
YKJ-262
Aster-A/C inhibitor
|
YKJ-262 is a potent, selective inhibitor of cholesterol transfer proteins Aster-A and Aster-C. |
| PC-27983 |
YKJ-86
Aster inhibitor
|
YKJ-86 is a potent, pan-inhibitor of cholesterol transfer proteins Aster-A, -B, and -C, effectively blocks Aster-mediated cholesterol transport in a concentration-dependent manner and completely inhibits cholesterol transport at 10 uM in CHO-K1 cells. |
| PC-27982 |
YKJ-305
Aster-C inhibitor
|
YKJ-305 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-C, blocks cholesterol transfer by Aster-C and inhibits fasting-induced PM-to-ER cholesterol transfer. |
| PC-27981 |
YKJ-124
Aster-A inhibitor
|
YKJ-124 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-A without affecting other cholesterol transport pathways, attenuates the suppression of nuclear SREBP2 by cyclodextrin-cholesterol in CHO cells, increases plasma membrane accessible cholesterol and potentiates store-operated Ca2+ entry in Th17 cells. |
| PC-27972 |
Z250-1659
CAS 1242982-27-9
|
Z250-1659 ((±)-Z250-1659) is a synthetic lethal compound against BAP1-deficient mesothelioma cells. |
| PC-27934 |
8015-P2
Mitofusin activator
|
8015-P2 is a potent and effective mitofusin activator with EC50 of 623 pM as fusogenic factor, allosterically activate mitofusins 1 and 2 (MFN1 and MFN2), demonstrates rapid reversal of sensory and motor neuron dysfunction in an Mfn2 T105M knock-in mouse model of Charcot-Marie-Tooth disease type 2 A (CMT2A). |
