A10P3C

Chemical Structure : A10P3C

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货号: PC-28436Not For Human Use, Lab Use Only.

A10P3C is a potent, isoform-selective inhibitor of prolyl hydroxylase EGLN2, effectively suppresses breast cancer cell proliferation, migration and invasion, induces G1 cell cycle arrest and cellular senescence through on-target EGLN2 inhibition.

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生物&药学活性

A10P3C is a potent, isoform-selective inhibitor of prolyl hydroxylase EGLN2, effectively suppresses breast cancer cell proliferation, migration and invasion, induces G1 cell cycle arrest and cellular senescence through on-target EGLN2 inhibition.

物理化学性质&存储条件

分子量	593.56
分子式	C21H28N3O11PS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-((4-ethoxyphenyl)sulfonyl)piperazine-1-carbonyl)-6-(N-methoxy-N-methylsulfamoyl)phenyl dihydrogen phosphate

参考文献

1. Liang Q, et al. Proc Natl Acad Sci U S A. 2026 Oct 6;123(40):e2613915123.

A10P3C

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物理化学性质&存储条件

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A10P3C

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