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首页-小分子抑制剂&激动剂-Others-Other Targets-FOXC1-I4
FOXC1-I4

Chemical Structure : FOXC1-I4

CAS No.: 3037987-36-0

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FOXC1-I4

货号: PC-28411Not For Human Use, Lab Use Only.

FOXC1-I4 is a small-molecule inhibitor of Forkhead box C1 (FOXC1), binds FOXC1 (SPR KD=2.68 uM) and suppresses FOXC1 transcriptional activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

FOXC1-I4 is a small-molecule inhibitor of Forkhead box C1 (FOXC1), binds FOXC1 (SPR KD=2.68 uM) and suppresses FOXC1 transcriptional activity.
FOXC1-I4 reduced A549 cell migration and invasion in a concentration-dependent manner at 2, 4, and 8 μM.
FOXC1-I4 suppresses lung cancer metastasis in vitro and in vivo.

物理化学性质&存储条件

分子量 387.48
分子式 C25H25NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-2-(4-(3-hydroxy-3-phenylprop-1-en-1-yl)phenyl)-N-(4-hydroxybenzyl)-N-methylacetamide

参考文献

1. Cao S, et al. Front Pharmacol. 2026 Sep 10;17:1868681.

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