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NFAT inhibitor 14

Chemical Structure : NFAT inhibitor 14

CAS No.: 499999-31-4

NFAT inhibitor 14

货号: PC-28453Not For Human Use, Lab Use Only.

NFAT inhibitor 14 is a small-molecule calcineurin-nuclear factor of activated T cells (NFAT) signaling inhibitor, inhibits the nuclear translocation and transcriptional activity of both NFATc1 and NFATc2, suppresses NFAT-dependent cytokine production, and shows cellular immunosuppressive activities.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NFAT inhibitor 14 is a small-molecule calcineurin-nuclear factor of activated T cells (NFAT) signaling inhibitor, inhibits the nuclear translocation and transcriptional activity of both NFATc1 and NFATc2, suppresses NFAT-dependent cytokine production, and shows cellular immunosuppressive activities.

物理化学性质&存储条件

分子量 384.43
分子式 C20H17FN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(N-Benzylsulfamoyl)−4-fluoro-N-phenylbenzamide

参考文献

1. Hong JE, et al. Arch Pharm Res. 2026 Oct 9. doi: 10.1007/s12272-026-01638-5.

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