AKR-XI-85

Chemical Structure : AKR-XI-85

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货号: PC-28491Not For Human Use, Lab Use Only.

AKR-XI-85 is a potent, non-retinoid triazolopyrimidine Retinol-Binding Protein 4 (RBP4) antagonist with binding IC50 of 23 nM in SPA assay and 194 nM in TTR-RBP4 HTRF assay.

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生物&药学活性

AKR-XI-85 is a potent, non-retinoid triazolopyrimidine Retinol-Binding Protein 4 (RBP4) antagonist with binding IC50 of 23 nM in SPA assay and 194 nM in TTR-RBP4 HTRF assay.

物理化学性质&存储条件

分子量	401.39
分子式	C20H18F3N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [(3aR,6aS)-hexahydro-5-[2-(trifluoromethyl)phenyl]cyclopenta[c]pyrrol-2(1H)-yl][1,2,4]triazolo[1,5-a]pyrimidin-2-yl-, rel-

参考文献

1. Rinderspacher KA, et al. bioRxiv [Preprint]. 2026 Sep 21:2026.09.14.751502.

AKR-XI-85

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AKR-XI-85

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