Orniplabin (SMTP-7, Lemuplamor, Stachybotrys microspora triprenylphenol-7) | Plasminogen modulator, sEh inhibitor

Chemical Structure : Orniplabin

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Orniplabin (SMTP-7, Lemuplamor, Stachybotrys microspora triprenylphenol 7)

货号: PC-28510Not For Human Use, Lab Use Only.

Orniplabin (SMTP-7, Lemuplamor, Stachybotrys microspora triprenylphenol-7) is a fungal triprenyl phenol metabolite and plasminogen modulator, shows thrombolytic and anti-inflammatory effects, inhibits soluble epoxide hydrolase (sEH) to suppress inflammation, inhibits Cterm-EH and the Nterm-phos of sEH with IC50 of 23 uM and 6 uM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Orniplabin (SMTP-7, Lemuplamor, Stachybotrys microspora triprenylphenol-7) is a fungal triprenyl phenol metabolite and plasminogen modulator, shows thrombolytic and anti-inflammatory effects, inhibits soluble epoxide hydrolase (sEH) to suppress inflammation, inhibits Cterm-EH and the Nterm-phos of sEH with IC50 of 23 uM and 6 uM.

物理化学性质&存储条件

分子量	869.11
分子式	C51H68N2O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2,5-bis((2R,3S)-2-((E)-4,8-dimethylnona-3,7-dien-1-yl)-3,5-dihydroxy-2-methyl-7-oxo-3,4,7,9-tetrahydropyrano[2,3-e]isoindol-8(2H)-yl)pentanoic acid

参考文献

1. Matsumoto N, et al. J Biol Chem. 2014 Dec 26;289(52):35826-38.

2. Hu W, et al. Thromb J. 2012 Jan 9;10(1):2.

3. Shibata K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2011 Jul;384(1):103-8.

4. Shibata K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2010 Sep;382(3):245-53.