| Cat. No. |
Product Name |
Information |
| PC-24307 |
BPRPT0245
PTGR2 inhibitor
|
BPRPT0245 is a specific small-molecule inhibitor of prostaglandin reductase 2 (PTGR2) with IC50 of 8.92 nM, restores 15-keto-PGE2-dependent PPARγ trans-activation in HEK293T cells expressing recombinant PTGR2 with EC50 of 49.22 nM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 (JBZ-001) is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-23912 |
TN2008
SRSF1 inhibitor
|
TN2008 is an effective serine arginine-rich splicing factor 1 (SRSF1) inhibitor with IC50 of 144 uM, exhibits high affinity for recombinant SRSF1 with Kd of 5.13 uM in SPR assays. |
| PC-23857 |
VK-2019
EBNA1 inhibitor
|
VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma. |
| PC-23850 |
ALT-007
Serine palmitoyltransferase inhibitor
|
ALT-007 is a potent, selective and orally bioavailable inhibitor of serine palmitoyltransferase (SPT) with enzyme IC50 of 0.54 nM. |
| PC-23833 |
EOS301984
ENT1 inhibitor
|
EOS301984 (EOS-984) is a potent, selective equilibrative nucleoside transporter 1 (ENT1) antagonist with IC50 of 339.6 nM (human ENT1), 150-fold selectivity for ENT1 versus ENT2. |
| PC-23824 |
Paquinimod
S100A9 inhibitor
|
Paquinimod (ABR-215757) is a specific inhibitor of S100A9, inhibits S100A8/S100A9 binding to RAGE, reduces diabetes-induced thrombocytosis. |
| PC-23762 |
SH514
IRF4 inhibitor
|
SH514 is a specific small molecule inhibitor of interferon regulatory factor 4 (IRF4) with IC50 of 2.63 uM, inhibits proliferation of IRF4-high-expressing NCI-H929 and MM.1R MM cells with IC50 of 0.08 uM and 0.11 uM, respectively. |
| PC-23716 |
G3BP1 inhibitor 129
G3BP1/2 inhibitor
|
G3BP1 inhibitor #129 is a small molecule ligand of G3BP1/2 (Ras-GTPase-activating protein SH3 domain-binding protein 1/2), binds with G3BP1 NTF2L domain with SPR KD of 3.7 uM, prevents stress granules (SGs) formation by disrupting G3BP1/caprin1 interaction. |
| PC-23564 |
DRI-C21041
CD40-CD40L inhibitor
|
DRI-C21041 is a specific small molecule inhibitor of CD40-CD40L costimulatory interaction with IC50 of 0.31 uM in cell-free in vitro binding inhibition assay. |
