| Cat. No. |
Product Name |
Information |
| PC-26075 |
TeGG
UGT1A1 inhibitor
|
1,2,3,6-Tetragalloylglucose (TeGG) is a substrate competitive inhibitor of UDP-glucuronyltransferase UGT1A1, inhibits UGT1A1-mediated β-estradiol 3-glucuronidation and SN-38 glucuronidation with IC50 of 6.01 uM and 4.31 uM, respectively. |
| PC-26070 |
APL-4098
GCN2 inhibitor
|
APL-4098 is a potent, selective, ATP-binding site competitive GCN2 inhibitor with Ki of 4.39 nM in TR-FRET assays. |
| PC-26065 |
PSMA-617
PSMA inhibitor
|
PSMA-617 (Vipivotide tetraxetan) is a potent, high affinity prostate-specific membrane antigen (PSMA) inhibitor with Ki of 0.37 nM. |
| PC-25797 |
JPC0661
ΔFOSB inhibitor
|
JPC0661 is a specific small molecule direct inhibitor of AP1 transcription factor ΔdeltaFOSB (ΔFOSB), inhibits FOSB/JUND and ΔFOSB DNA-binding biochemically with IC50 of 9 uM and 52 uM respectively. |
| PC-25682 |
Ferovicin
FERONIA receptor inhibitor
|
Ferovicin is a specific small molecule inhibitor FERONIA (FER) receptor kinase with IC50 of 70 nM, selectively binds to the ATP-binding pocket of the kinase domain of FER and inhibits its kinase activity. |
| PC-25675 |
JNJ-9350
Spermine oxidase inhibitor
|
JNJ-9350 is a potent, selective Spermine oxidase (SMOX) inhibitor with IC50 of 8 nM for human SMOX (hSMOX), shows remarkable selectivity over hPAOX (>89-fold). |
| PC-25660 |
B32B3
VprBP inhibitor
|
B32B3 is a specific, small‐molecule inhibitor of DCAF1 (Vpr-binding protein, VprBP) with IC50 of 0.6 uM, selectively inhibits H2AT120p with IC50 of 0.5 uM. |
| PC-25656 |
EPIC-1042
PTRF-CAV1 inhibitor
|
EPIC-1042 is a potent, small molecule PTRF/Cavin1-caveolin-1 interaction inhibitor with IC50 of 38 uM, inhibits the binding of PTRF to Caveolin-1 (CAV1), resulting in decreased secretion of small extracellular vesicles (sEVs). |
| PC-25644 |
ISR activator A8
RIG-I binder, ISR activator
|
ISR activator A8 is a specific small molecule activator of integrated stress response (ISR) through the binding of the cytosolic pattern recognition receptor RIG-I, subsequently activates the heme-regulated inhibitor (HRI) ISR kinase independent of an interferon response. |
| PC-25634 |
ZDHHC2 inhibitor TTZ1
zDHHC2 inhibitor
|
zDHHC2 inhibitor TTZ1 (Tetrazole-1, TTZ-1) is a specific enzymatic inhibitor of palmitoyltransferase ZDHHC2, inhibits human zDHHC2-mediated substrate (SNAP25) S-acylation in vitro with IC50 of 4.7 uM. |
| PC-25627 |
Vav1 inhibitor AB19
Vav1 inhibitor
|
Vav1 inhibitor AB19 is a small molecule inhibitor of guanine nucleotide exchange factor Vav1 atypical C1 domain (Vav1C1), effectly inhibits proliferation of Vav1-expressing cells, inhibits growth of patient-derived organoids models of pancreatic cancer. |
| PC-25580 |
CIA1 free base
COUP-TFII inhibitor
|
CIA1 free base (COUP-TFII inhibitor A1) is a potent and specific inhibitor of COUP-TFII activity, inhibits COUP-TFII–driven NGFIA reporter expression with IC50 of 3.2 uM, disturbs COUP-TFII binding to FOXA1 to regulate target gene expression. |
