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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial

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Bacteria constitute a large domain of prokaryoticmicroorganisms. Antibiotics (also called antibacterials) are a type of antimicrobial drug used in the treatment and prevention of bacterial infections, a limited number of antibiotics also possess antiprotozoal activity. Together with vaccination, antibiotics have led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access have also led to their overuse, prompting bacteria to develop resistance.

A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. In vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.

 
 

Cat. No. Product Name Information
PC-42204

Erythromycin cyclocarbonate

A derivative of Erythromycin that inhibits protein synthesis of bacteria by binding to the 50S ribosome, shows activity against Gram-positive and some Gram-negative microorganisms..
PC-42323

Bicyclomycin benzoate

A broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium.

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