Cat. No. |
Product Name |
Information |
PC-42665 |
Gatifloxacin
Bacterial DNA gyrase inhibitor
|
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |
PC-42048 |
Faropenem daloxate
Beta-lactam antibiotic
|
Faropenem daloxate (Faropenem medoxil) is a daloxate ester prodrug of Faropenem with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes, a beta-lactam antibiotic. |
PC-42714 |
PA-824
Antibiotic
|
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid. |
PC-24836 |
Isoniazid
Antibiotic
|
Isoniazid (INH) is an antibiotic with bactericidal activity, has anti-tuberculostatic activity. |
PC-24835 |
Levofloxacin
Antibiotic
|
Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria, inhibits DNA gyrase and Topoisomerase IV. |
PC-24834 |
Streptomycin
Antibiotic
|
Streptomycin (Agrimycin, Streptomycin A) is an effective antibiotic against M. tuberculosis, binds strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. |
PC-24832 |
TPN-0157345
MmpL3 inhibitor
|
TPN-0157345 is a small molecule inhibitor of Mycobacterium tuberculosis (M.tb) mycolic acid exporter MmpL3, targets cell wall biosynthesis, inhibits aerobically cultured M. tuberculosis H37Rv with IC90 of 3.3 uM. |
PC-24831 |
ANT3310 sodium
Serine β-Lactamase inhibitor
|
ANT3310 sodium is a potent, covalent broad-spectrum serine β-Lactamase inhibitor with IC50 of 1-175 nM against a panel of serine β-Lactamases. |
PC-24816 |
DRILS-1398
M.tb chorismate mutase inhibitor
|
DRILS-1398 is a potent inhibitor of M.tb chorismate mutase (M.tb-CM) with IC50 of 3.0 uM, demonstrates efficacy against multi-drug resistant M.tb strains (MIC=4 ug/mL), inhibits M.tb amino acid biosynthetic pathway. |
PC-24738 |
Tarocin B
TarO inhibitor
|
Tarocin B is a specific inhibitor of UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (TarO) with IC50 of 0.41 uM, inhibits the first step in wall teichoic acid biosynthesis, restore β-lactam efficacy against MRSA. |
PC-24737 |
Tarocin A
TarO inhibitor
|
Tarocin A is a specific inhibitor of UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (TarO) with IC50 of 0.18 uM, inhibits the first step in wall teichoic acid biosynthesis, restore β-lactam efficacy against MRSA. |
PC-24471 |
TU-514
LpxC inhibitor
|
TU-514 is a substrate-analog inhibitor of zinc-dependent UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with Ki of 3.9 uM for E. coli LpxC and IC50 of 7.0 uM (A. aeolicus LpxC) |