Cat. No. |
Product Name |
Information |
PC-42192 |
DprE1-IN-25
DprE1 inhibitor
|
DprE1-IN-25 is a potent, noncovalent DprE1 inhibitor with IC50 of 43 nM, shows activity against Mycobacterium tuberculosis (Mtb) in vitro with MIC of 0.39 uM. |
PC-45087 |
AFN-1252
FabI inhibitor
|
AFN-1252 (API-1252, Debio 1452) is a potent inhibitor of bacterial enoyl-ACP reductase FabI. |
PC-45070 |
Relebactam
β-lactamase inhibitor
|
Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro. |
PC-45372 |
Dalbavancin
Antibiotic
|
Dalbavancin (MDL-63397, BI-397) is a novel second-generation lipoglycopeptide antibiotic with MIC90 values of 0.06 μg/mL and 0.25 μg/mL for Staphylococcus aureus and Bacillus anthracis, respectively. |
PC-42302 |
Q203
Mtb QcrB inhibitor
|
Telacebec (Q203, IAP6) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB, inhibits M. tuberculosis H37Rv with MIC50 of of 2.7 nM. |
PC-45436 |
Walrycin B
Baterial WalR regulator, 3CLpro inhibitor
|
Walrycin B is a baterial WalR response regulator, an analogue of toxoflavin and a potent SARS-CoV-2 3CLpro inhibitor with IC50 of 0.26 uM. |
PC-42236 |
BM212
MmpL3 inhibitor
|
BM212 is a novel antitubercular agent that possesses strong inhibitory activity against both Mycobacterium tuberculosis (MIC=0.7-1.5 ug/ml) and some nontuberculosis mycobacteria, inhibits transport activity of MmpL3. |
PC-45367 |
Fidaxomicin
Antibiotic
|
Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL. |
PC-42715 |
Delamanid
|
Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB. |
PC-45263 |
Azathramycin
Antibiotic
|
Azathramycin is a macrolide antibiotic that effectively inhibits tumor angiogenesis by suppressing VEGFR2-mediated signaling pathways in lung cancer. |
PC-45638 |
Ribocil-C
FMN riboswitch inhibitor
|
Ribocil-C is a highly selective inhibitor of the FMN riboswitch that controls expression of de novo riboflavin (Vitamin B2) biosynthesis in Escherichia coli. |
PC-42665 |
Gatifloxacin
Bacterial DNA gyrase inhibitor
|
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV. |