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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-RNPA2000
RNPA2000

Chemical Structure : RNPA2000

CAS No.: 329214-04-2

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RNPA2000 (RNPA 2000)

货号: PC-63264Not For Human Use, Lab Use Only.

RNPA2000 is a small-molecule inhibitor of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing (IC50=130 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    RNPA2000 is a small-molecule inhibitor of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing (IC50=130 uM).
    RNPA2000 inhibits both RnpA-associated RNA degradation and tRNA maturation activities both in vitro and within S. aureus.

    物理化学性质&存储条件

    分子量 361.416
    分子式 C17H19N3O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-(2-(4-isopropylphenoxy)acetyl)hydrazine-1-carbonothioyl)furan-2-carboxamide

    参考文献

    1. Eidem TM, et al. Antimicrob Agents Chemother. 2015 Apr;59(4):2016-28.

    2. Lounsbury N, et al. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1127-1131.

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