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Taniborbactam

Chemical Structure : Taniborbactam

CAS No.: 1613267-49-4

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Taniborbactam (VNRX-5133, VNRX5133)

货号: PC-63297Not For Human Use, Lab Use Only.

Taniborbactam (VNRX5133) is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Taniborbactam (VNRX5133) is a highly potent and specific beta-lactamase inhibitor with IC50 of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2 respectively.
    Taniborbactam (VNRX5133) shows activity against Gram-negative bacteria and used in combination with a licensed beta-lactam antibiotic.

    物理化学性质&存储条件

    分子量 389.259
    分子式 C19H28BN3O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(2-((1r,4r)-4-((2-aminoethyl)amino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid

    参考文献

    1. Krajnc A, et al. J Med Chem. 2019 Sep 26;62(18):8544-8556.

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