Cat. No. |
Product Name |
Information |
PC-22835 |
Cefiderocol
Antibiotic
|
Cefiderocol (CFDC, S-649266) is a siderophore cephalosporin antibiotic, has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50 of <2 ug/mL. |
PC-22815 |
VOMG
M. abscessus inhibitor
|
VOMG is a small molecule compound active against Mycobacterium abscessus (Mab, MIC=0.25 ug/mL) and other pathogens by inhibiting cell division. |
PC-22813 |
TST1N-224
S. aureus VraRC inhibitor
|
TST1N-224 is a potent inhibitor targeting the response regulator VraRC of S. aureus, inhibits the formation of the VraRC-DNA complex with IC50 of 60.2 uM, shows strong binding to VraRC (KD=23.4 uM), enhances the susceptibility of vancomycin-intermediate S. aureus (VISA) to both vancomycin and methicillin. |
PC-22725 |
Kanamycin sulfate
Antibiotic
|
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. |
PC-22724 |
Kanamycin
Antibiotic
|
Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. |
PC-22717 |
PQD-1
DHFR inhibitor
|
PQD-1 is a DHFR inhibitor with activity against Mycobacterium tuberculosis, PQD-1 synergizes with the dihydropteroate synthase (DHPS) inhibitor sulfamethoxazole (SMX). |
PC-22699 |
C10-AMS
AasS inhibitor
|
C10-AMS is an acyl adenylate mimic and acyl-acyl carrier protein synthetase (AasS, acyl-ACP synthetase) inhibitor with Ki of 0.6 uM, inhibit the AasS-catalyzed loading of fatty acids onto acyl carrier protein (ACP). |
PC-22691 |
Trypyricin 1
Antibacterial
|
Trypyricin 1 is a broad-spectrum antibacterial with MIC of 0.5 ug/mL for S. aureus MRSA252 (MRSA), membrane fluidizer, re-sensitizes methicillin-resistant MRSA to β-lactam antibiotics both in vitro and in mice. |
PC-22663 |
Trimethoprim
DHFR inhibitor
|
Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase (DHFR) inhibitor, shows acitvity against a wide range of Gram-positive and Gram-negative aerobic bacteria. |
PC-22662 |
Brodimoprim
DHFR inhibitor
|
Brodimoprim (Ro 10-5970) is a trimethoprim analogue and orally active dihydrofolate reductase (DHFR) inhibitor, shows acitvity against a wide range of Gram-positive and Gram-negative aerobic bacteria. |
PC-22658 |
KSP-1007
β-lactamase inhibitor
|
KSP-1007 is a potent, broad-spectrum boronic acid β-lactamase inhibitor, strongly inhibits class A carbapenemase KPCs with Ki app values of 0.836-2.19 nM, inhibits all β-lactamases from classes A, B, C, and D, enhances meropenem against carbapenem-resistant Gram-negative bacteria. |
PC-22624 |
AN2718
KPC-2 inhibitor
|
AN2718 is a small molecule inhibitor of the catalytic activity of the Klebsiella pneumoniae carbapenemase (KPC-2) enzyme with IC50 of 0.5 uM and ITC Kd of 86.3 nM, exhibit synergistic antimicrobial effect with Meropenem. |