| Cat. No. |
Product Name |
Information |
| PC-61750 |
MmpL3 inhibitor C215
MmpL3 inhibitor
|
C215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3) with MIC90 of 16 uM against M. tuberculosis. |
| PC-61436 |
CRS3123
MetRS inhibitor
|
CRS3123 (REP 3123) is a novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases (MetRS) in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI). |
| PC-61388 |
Macozinone
DprE1 inhibitor
|
Macozinone (PBTZ-169, PBTZ169) is a potent, second-generation antituberculosis agent that inhibits DprE1 and displays nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. |
| PC-61371 |
Contezolid
Antibiotic
|
Contezolid (MRX I) is an orally active oxazolidinone agent with antibacterial activity Gram-positive pathogens, including MRSA, penicillin-PRSP, PISP, and vancomycin-resistant enterococci (VRE) with MIC of 0.25-4 ug/mL. |
| PC-61295 |
Murepavadin
Antibiotic, MRGPRX2 agonist
|
Murepavadin (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic, activates mast cells via MRGPRX2 and MrgprB2. |
| PC-61266 |
KKL-40
Antibacterial
|
KKL-40 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture. |
| PC-61265 |
KKL-10
Antibacterial
|
KKL-10 is a small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture. |
| PC-70255 |
INP-0400
C. trachomatis type III secretion inhibitor
|
INP-0400 (INP0400) is a small-molecule inhibitor of type III secretion (TTS, T3SS) in Chlamydia trachomatis, inhibits intracellular replication and infectivity of C. trachomatis at micromolar concentrations, inhibits C. trachomatis reticulate bodies (RB) multiplication, binds effectively with YspD. |
| PC-70355 |
VU0038882
S. aureus HssRS activator
|
VU0038882 is a small molecule activator of S. aureus HssRS (heme sensor system) that induces endogenous heme biosynthesis by perturbing central metabolism. |
| PC-70354 |
KKL-35
Antibacterial, trans-translation inhibitor
|
KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM. |
| PC-70348 |
TCA1
DprE1 inhibitor
|
TCA1 is a small molecule with activity against drug-resistant and persistent tuberculosis, inhibits DprE1 and MoeW, enzymes involved in cell wall and molybdenum cofactor biosynthesis. |
| PC-70341 |
DSM 74
Pf DHODH inhibitor
|
DSM 74 is a potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity. |