Relebactam | β-lactamase inhibitor | Probechem Biochemicals

Chemical Structure : Relebactam

CAS No.: 1174018-99-5

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Relebactam (MK-7655, MK7655)

货号: PC-45070Not For Human Use, Lab Use Only.

Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.
Relebactam (MK-7655) effectively restored imipenem's activity against imipenem-resistant Pseudomonas and Klebsiella strains at clinically achievable concentrations.
Relebactam (MK-7655) reduces imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L at a concentration of 4 mg/L.

物理化学性质&存储条件

分子量	348.3754
分子式	C12H20N4O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sulfuric acid, mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester

参考文献

1. Hirsch EB, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3753-7.

2. Blizzard TA, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):780-5.

3. Livermore DM, et al. J Antimicrob Chemother. 2013 Oct;68(10):2286-90.

Relebactam (MK-7655, MK7655)

生物&药学活性

物理化学性质&存储条件

参考文献

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Relebactam (MK-7655, MK7655)

生物&药学活性

物理化学性质&存储条件

参考文献

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