Cat. No. |
Product Name |
Information |
PC-21529 |
Inhibitor 21272541
FabI inhibitor
|
Inhibitor 21272541 is a small molecule inhibitor against the enoyl-acyl carrier protein reductase-FabI protein of Acinetobacter baumannii. |
PC-21349 |
EPM35
Bacterial efflux pump modulator
|
EPM35 (Efflux pump modulator 35) is a small molecule that bind AcrB (KD=0.29 uM), inhibit AcrAB-TolC and modulates bacterial efflux pump activity, reduces bacterial intracellular load. |
PC-21216 |
C. difficile inhibitor 57
C. difficile inhibitor
|
C. difficile inhibitor 57 is a potent, selective, narrow-spectrum antibacterial against Clostridioides difficile with MIC50 of 0.5 ug/mL, targets cell-wall synthesis. |
PC-21141 |
KKL-55
Bacterial EF-Tu inhibitor
|
KKL-55 is a specific small molecule inhibitor of bacterial trans-translation by binding to longation factor thermo-unstable (EF-Tu, Kd=2 uM), inhibits binding between EF-Tu and tmRNA but not between EF-Tu and tRNA, has broad-spectrum antibiotic activity. |
PC-21137 |
SAV13
SaeR inhibitor
|
SAV13 is a selective small molecule inhibitor of S. aureus exoprotein expression regulator (SaeR) withEC50 of 1.06 uM in luciferase assays, reduces expression of hla and other virulence factors. |
PC-21136 |
HR3744
SaeR inhibitor
|
HR3744 is a selective small molecule inhibitor of S. aureus exoprotein expression regulator (SaeR) withEC50 of 10 uM in saeP1 promoter assays, reduces expression of hla and other virulence factors. |
PC-21120 |
Compound 5-6
FtsW inhibitor
|
Compound 5-6 (FtsW inhibitor 5-6) is a specific small molecule inhibitor of bacterial cell wall polymerase FtsW, competes with Lipid II for binding to FtsW with Ki of 0.8 uM, has an MIC of 1 μg /mL against S. aureus. |
PC-21050 |
Clovibactin
Antibiotic
|
Clovibactin is a novel depsipeptide antibiotic, exhibits antibacterial activity against a broad range of Gram-positive pathogens (MIC, 1-2 ug/mL, ATCC 33591 MRSA), Clovibactin targets cell wall biosynthesis. |
PC-21019 |
LPC-233
LpxC inhibitor
|
LPC-233 (LPC233) is a highly potent and specific inhibitor of UDP-3-O-(R-3-hydroxyacyl)-N-acetylglucosamine deacetylase LpxC (Ki=8.9 pM), specifically inhibits lipid A synthesis and displays outstanding antibiotic activities. |
PC-20990 |
ND-011992
Cyt‐bd inhibitor
|
ND-011992 is a cytochrome bd oxidase (Cyt‐bd) inhibitor, inhibits Mycobacterium tuberculosis respiratory complex I with IC50 of 0.12 uM, targets respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases. |
PC-20704 |
Min-1
Antibacterial agent
|
Min-1 is small molecule that inhibits growth of Gram-positive bacteria by targeting the cell envelope, Min-1 is a novel inhibitor of bacterial growth, reduces cell size in Bacillus subtilis. |
PC-20696 |
SK-017154-O
PelA inhibitor
|
SK-017154-O is a specific and noncompetitive inhibitor of PelA, specifically inhibits PelA esterase activity with IC50 of 11 uM, inhibits Pel-dependent PA14 biofilms with IC50 of 1.8 uM. |