| Cat. No. |
Product Name |
Information |
| PC-27654 |
Cilastatin sodium
DPEP1 inhibitor
|
Cilastatin sodium (MK-0791) is a reversible, competitive renal dehydropeptidase I (DPEP1) inhibitor with IC50 of 0.1 uM, also inhibits bacterial metallob-lactamase enzyme CphA, suppresses the invasion and metastasis of DPEP1-expressing cells. |
| PC-27653 |
Cilastatin
DPEP1 inhibitor
|
Cilastatin (MK-0791) is a reversible, competitive renal dehydropeptidase I (DPEP1) inhibitor with IC50 of 0.1 uM, also inhibits bacterial metallob-lactamase enzyme CphA, suppresses the invasion and metastasis of DPEP1-expressing cells. |
| PC-27588 |
Ceftazidime
β-lactam antibiotic
|
Ceftazidime (Fortaz, GR20263) is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against resistant bacteria such as Pseudomonas aeruginosa, a β-lactam antibiotic. |
| PC-27563 |
TTS29
Type III secretion inhibitor
|
TTS29 is a small molecule inhibitor of S. typhimurium type III secretion system (T3SS), disrupts the needle assembly of Yersinia spp., P. aeruginosa and Francisella novicida, block the secretion and virulence functions of a wide array of animal and plant Gram-negative bacterial pathogens, such as Y. spp., P. aeruginosa and Francisella novicida. |
| PC-27562 |
INP0010
Type III secretion inhibitor
|
INP0010 is a small-molecular inhibitor of bacterial virulence factor, inhibits type III secretion system (T3SS), prevents virulence factor-mediated replication of S. Typhimurium in macrophage-like RAW264.7 cells. |
| PC-27561 |
MBX1641
Type III secretion inhibitor, YspD ligand
|
MBX1641 (MBX-1641) is a small-molecule inhibitor of bacterial type III secretion (TTS, T3SS), not only bind effectively with YspD, but also bind to the functionally important domains of YspD and might lead to the functional inactivation of YspD, inhibits TIIISS effector protein ExoS in P. aeruginosa. |
| PC-27434 |
Saeamid-1
MRSA SaeS inhibitor
|
Saeamid-1 is a potential antivirulence compound and SaeS-targeting antagonist against methicillin-resistant Staphylococcus aureus (MRSA), reduces hemolytic activity and biofilm biomass while having only limited effects on MRSA growth. |
| PC-27401 |
Geneticin
Antibiotic
|
Geneticin (G418, Antibiotic G-418) is an aminoglycoside antibiotic with a structure similar to gentamicin, is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis. |
| PC-27400 |
Pefloxacin
Antibiotic
|
Pefloxacin is a fluoroquinolone antibiotic used for various bacterial infections, inhibits Plasmodium falciparum in vitro, inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase. |
| PC-27399 |
Amifloxacin
Antibiotic
|
Amifloxacin (WIN 49375) is an quinolone carboxylic acid antibacterial agent with MIC of 4 ug/mL against aminoglycoside-resistant Pseudomonas aeruginosa, shows broad activity for gentamicin-resistant gram-negative bacilli. |
| PC-27374 |
OSSL-632214
Mtb TrxB2 inhibitor
|
OSSL-632214 (OSSL_632214) is a potent anti-Mtb compound with MIC of 3.13-6.25 μg/mL in vitro, possibly acts by targeting Thioredoxin reductase (TrxB2, Rv3913) and inducing lipid peroxidation in Mtb. |
| PC-27279 |
Mtb IMPDH2-IN-2
Mtb IMPDH2 inhibitor
|
MtbIMPDH2-IN-2 is a potent, selective Mycobacterium tuberculosis (Mtb) inosine 5'-monophosphate dehydrogenase 2 (MtbIMPDH2) inhibitor with IC50 of 12 nM, and MIC of 12 uM for Mtb, blocks the biosynthesis of guanine nucleotides. |
