Cefiderocol | Antibiotic | Probechem Biochemicals

Chemical Structure : Cefiderocol

CAS No.: 1225208-94-5

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Cefiderocol (CFDC, S-649266, S649266)

货号: PC-22835Not For Human Use, Lab Use Only.

Cefiderocol (CFDC, S-649266) is a siderophore cephalosporin antibiotic, has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50 of <2 ug/mL.

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生物&药学活性

Cefiderocol (CFDC, S-649266) is a siderophore cephalosporin antibiotic, has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50 of <2 ug/mL.
Cefiderocol shows antibacterial activity against carbapenem-resistant strains of Enterobacteriaceae and nonfermenting bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii.
Cefiderocol has affinity mainly for penicillin-binding protein 3 (PBP3) of Enterobacteriaceae and nonfermenting bacteria similar to that of ceftazidime.

物理化学性质&存储条件

分子量	752.21
分子式	C30H34ClN7O10S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-3-((1-(2-(2-chloro-3,4-dihydroxybenzamido)ethyl)pyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

参考文献

1. Ito A, et al. Antimicrob Agents Chemother. 2017 Dec 21;62(1).

Cefiderocol (CFDC, S-649266, S649266)

生物&药学活性

物理化学性质&存储条件

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Cefiderocol (CFDC, S-649266, S649266)

生物&药学活性

物理化学性质&存储条件

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