Cat. No. |
Product Name |
Information |
PC-35267 |
VXc-486
Gyrase B inhibitor
|
VXc-486 (SPR719) is a novel inhibitor of gyrase B, potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis in vitro with MICs of 0.03-0.30 μg/ml and 0.08-5.48 μg/ml, respectively. |
PC-35157 |
Q151
Mtb IMPDH2 inhibitor
|
Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (Mtb IMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity. |
PC-35094 |
P516-0475
PepO inhibitor
|
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM). |
PC-35073 |
JCP251
FphB inhibitor
|
JCP251 is a selective small molecule inhibitor of S. aureus serine hydrolase FphB, effectively reduces infectivity in vivo. |
PC-35006 |
VB-82252
TcdB inhibitor
|
VB-82252 is a highly potent, orally active inhibitor of C. difficile toxins TcdA and TcdB, potently inhibits UDP glucose hydrolysis activity of TcdB (IC50=32 nM). |
PC-63580 |
MsbA inhibitor TBT1
MsbA inhibitor
|
MsbA inhibitor 1 is a novel small molecule lipopolysaccharide biogenesis inhibitor, inhibits MsbA, an ATP-dependent flippase that translocates LPS across the inner membrane. |
PC-63533 |
XF-73
Antibacterial
|
XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus. |
PC-63482 |
G907
MsbA inhibitor
|
G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM. |
PC-63480 |
HMPC
Antibacterial
|
HMPC is a novel bacteriostatic agent that shows bacteriostatic activity against S. aureus (MIC=4 μg/ml) and rescues Caenorhabditis elegans from S. aureus infection. |
PC-63351 |
LYS228
Antibacterial
|
LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml. |
PC-63325 |
ANT431 sodium
Metallo-β-lactamase inhibitor
|
ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
PC-63324 |
ANT431
Metallo-β-lactamase inhibitor
|
ANT431 is a novel potent metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |