Compound 11726148

Chemical Structure : Compound 11726148

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货号: PC-72404Not For Human Use, Lab Use Only.

Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex.

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生物&药学活性

Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex.
Compound 11726148 demonstrated in vivo activity in an acute model of murine TB.

物理化学性质&存储条件

分子量	255.287
分子式	C11H11F2N3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(ethylthio)-7,8-difluoro-N-methylquinazolin-4-amine

参考文献

1. Andréanne Lupien, et al. PLoS Pathog. 2020 Jan 23;16(1):e1008270.