Cat. No. |
Product Name |
Information |
PC-21952 |
RO7075573
Antibiotic
|
RO7075573 is a small-molecule, tethered macrocyclic peptide antibiotic targeting the lipopolysaccharide transporter, has MIC of 0.12 ug/mL A. baumannii ATCC 19606. |
PC-21856 |
Iboxamycin
Antibiotic
|
Iboxamycin (IBX) is a broad-spectrum ribosome-binding antibiotic with potent activity against Gram-positive and Gram-negative bacteria overcomes bacterial multidrug resistance. |
PC-21855 |
Cresomycin
Antibiotic
|
Cresomycin (CRM) is a bridged macrobicyclic antibiotic via inhibiting bacterial ribosome, shows broad efficacy of CRM against clinical isolates of MDR Gram-negative pathogens differentiates the synthetic macrobicyclic class from traditional lincosamides. |
PC-21823 |
AM4085
FmlH Lectin inhibitor
|
AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM. |
PC-21765 |
Trovafloxacin
PANX1 inhibitor
|
Trovafloxacin is a broad-spectrum quinolone antibiotic, blocks the DNA gyrase and topoisomerase IV activity, also is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with IC50 of 4 uM for PANX1 inward current. |
PC-21689 |
BDM91288
AcrB efflux pump inhibitor
|
BDM91288 is a pyridylpiperazine-based AcrB efflux pump inhibitor, potentiate the activity of a panel of antibiotics against K. pneumoniae. |
PC-21682 |
JSF-3269
E. faecium inhibitor
|
JSF-3269 is a small molecule antibacterial inhibitor against Enterococcus faecium with MIC of 1.9-3.8 uM and minimal bactericidal concentration (MBC) of 7.7-15 uM. |
PC-21661 |
TBAJ-5307
Non-tuberculous mycobacteria inhibitor
|
TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria (NTM) inhibitor targeting FO-domain of F1FO-ATP synthase, shows MIC50 of 4.5 nM and 6 nM against the Mab subsp. abscessus smooth strain and rough strain respectively. |
PC-21654 |
BB2-50F
M. tuberculosis inhibitor
|
BB2-50F is a bactericidal inhibitor of M. tuberculosis with MIC value of 8 uM (H37Rv), inhibits succinate dehydrogenase and the F1Fo-ATP synthase. |
PC-21552 |
SMT-738
LolCDE inhibitor
|
SMT-738 is a small-molecule inhibitor of bacterial lipoprotein transport complex (LolCDE), shows potent and highly selective antimicrobial activity. |
PC-21549 |
BFA1
FixLJ inhibitor
|
BFA1 is a specific small-molecule activator of Burkholderia FixLJ signaling pathway, inhibit the virulence of multiple pathogenic Burkholderia species. |
PC-21545 |
MSU-43085
Mtb MmpL3 inhibitor
|
MSU-43085 is a potent, orally bioavailable inhibitor of Mycobacterium tuberculosis (Mtb, EC50=120 nM) and M. abscessus survival, targets MmpL3. |