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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-PBZ1587
PBZ1587

Chemical Structure : PBZ1587

CAS No.: 2247719-94-2

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PBZ1587 (PBZ 1587)

货号: PC-22849Not For Human Use, Lab Use Only.

PBZ1587 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 0.44 uM in MDH refolding assay, binds at the GroEL ring–ring interface (RRI).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PBZ1587 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 0.44 uM in MDH refolding assay, binds at the GroEL ring–ring interface (RRI).

物理化学性质&存储条件

分子量 575.07
分子式 C24H19ClN4O5S3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(4-((4-(aminomethyl)phenyl)sulfonamido)phenyl)benzo[d]oxazol-5-yl)-5-chlorothiophene-2-sulfonamide

参考文献

1. Jack Godek, et al. J Am Chem Soc. 2024 Jul 31;146(30):20845-20856.

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