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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Bedaquiline fumarate
Bedaquiline fumarate

Chemical Structure : Bedaquiline fumarate

CAS No.: 845533-86-0

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Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate)

货号: PC-63299Not For Human Use, Lab Use Only.

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

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25 mg ￥1180 In stock
100 mg ￥2280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

物理化学性质&存储条件

分子量 671.588
分子式 C36H35BrN2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid

参考文献

1. Jang JC, et al. J Microbiol. 2017 Apr 20.

2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).

3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.

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