LYS228 | Antibacterial | Probechem Biochemicals

Chemical Structure : LYS228

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LYS228 (LYS-228, LYS 228)

货号: PC-63351Not For Human Use, Lab Use Only.

LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.

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生物&药学活性

LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/mL.
LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types.

物理化学性质&存储条件

分子量	518.472
分子式	C16H18N6O10S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((((Z)-1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropane-1-carboxylic acid

参考文献

1. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755.

LYS228 (LYS-228, LYS 228)

生物&药学活性

物理化学性质&存储条件

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LYS228 (LYS-228, LYS 228)

生物&药学活性

物理化学性质&存储条件

参考文献

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