TBA-354 |CAS:1257426-19-9 Probechem Biochemicals

Chemical Structure : TBA-354

CAS No.: 1257426-19-9

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TBA-354 (TBA354)

货号: PC-43057Not For Human Use, Lab Use Only.

TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
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生物&药学活性

TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.

物理化学性质&存储条件

分子量	436.3414
分子式	C19H15F3N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 46 mg/mL
Chemical Name/SMILES	5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy]-, (6S)-

参考文献

1. Kmentova I, et al. J Med Chem. 2010 Dec 9;53(23):8421-39.

2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.

3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.

TBA-354 (TBA354)

生物&药学活性

物理化学性质&存储条件

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TBA-354 (TBA354)

生物&药学活性

物理化学性质&存储条件

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