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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Pexiganan
Pexiganan

Chemical Structure : Pexiganan

CAS No.: 147664-63-9

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Pexiganan (MSI-78)

货号: PC-27793Not For Human Use, Lab Use Only.

Pexiganan (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.

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5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pexiganan (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.

物理化学性质&存储条件

分子量 2477.18
分子式 C122H210N32O22
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

L-Lysinamide, glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl-L-lysyl-

参考文献

1. Ge Y, et al. Antimicrob Agents Chemother. 1999 Apr;43(4):782-8.

2. Fuchs PC, et al. Antimicrob Agents Chemother. 1998 May;42(5):1213-6.

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