| Cat. No. |
Product Name |
Information |
| PC-42741 |
UNC0321
G9a inhibitor
|
UNC0321 (UNC-0321) is a highly potent, selective histone methyltransferase G9a inhibitor with Ki of 63 pM. |
| PC-45092 |
MI-503
Menin-MLL inhibitor
|
MI-503 (MI 503) is a highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM. |
| PC-42907 |
3-Deazaneplanocin A hydrochloride
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) hydrochloride is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42587 |
3-Deazaneplanocin A
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42923 |
MM-102 trifluoroacetate
MLL1/WDR5 inhibitor
|
MM-102 trifluoroacetate is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-42922 |
MM-102
MLL1/WDR5 inhibitor
|
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-45489 |
PFI-2 hydrochloride
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-45488 |
PFI-2
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-28195 |
MM-401 TFA
MLL1/WDR5 inhibitor
|
MM-401 TFA is a potent inhibitor of MLL1/WDR5 protein-protein interaction with IC50 of 0.9 nM. |
| PC-28194 |
MS2928 TFA
SETD8 inhibitor
|
MS2928 TFA is a potent and selective SETD8 covalent inhibitor, inhibits SETD8 methyltransferase activity with IC50 of 0.14 uM, covalently modifies SETD8 at Cys311. |
| PC-28193 |
ND-L11B TFA
NSD2 degrader
|
ND-L11B TFA is an effective degrader of RE-IIBP and NSD2-long, effectively induces NSD2 degradation with DC50 of 1.48 and 0.80 uM in KMS11 MM cell line, reduces H3K36me2 level in cancer cells. |
| PC-28192 |
GSK2807 Trifluoroacetate
SMYD3 inhibitor
|
GSK2807 Trifluoroacetate (GSK 2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM and IC50 of 130 nM. |
