MM-102 |CAS:1417329-24-8 Probechem Biochemicals

Chemical Structure : MM-102

CAS No.: 1417329-24-8

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MM-102 (MM102;MM 102)

货号: PC-42922Not For Human Use, Lab Use Only.

MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.

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5 mg	￥1480	In stock
10 mg	￥2280	In stock
25 mg	￥3880	In stock
50 mg	￥5980	In stock
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生物&药学活性

MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
MM-102 effectively decreases the expression of HoxA9 and Meis-1.
MM-102 specifically inhibits cell growth and induces apoptosis in leukemia cells harboring MLL1 fusion proteins.

物理化学性质&存储条件

分子量	669.8049
分子式	C35H49F2N7O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclopentanecarboxamide, 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-

参考文献

1. Karatas H, et al. J Am Chem Soc. 2013 Jan 16;135(2):669-82.

MM-102 (MM102;MM 102)

生物&药学活性

物理化学性质&存储条件

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MM-102 (MM102;MM 102)

生物&药学活性

物理化学性质&存储条件

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