Cat. No. |
Product Name |
Information |
PC-20832 |
SETDB1 activator (R,R)-59
SETDB1 activator
|
(R,R)-59 is a small-molecule ligand activator for methyltransferase SETDB1 Triple Tudor Domain (3TD reader domain) with binding IC50 of 1.2 uM in TR-FRET assays, specifically promotes in vitro SETDB1-mediated methylation of lysine 64 of protein kinase Akt1. |
PC-20564 |
M-808
menin-MLL inhibitor
|
M-808 (M808) is a highly potent, selective and covalent inhibitor of menin-MLL interaction with binding IC50 of 2.6 nM, forms a covalent bond with Cys329 in menin. |
PC-20514 |
Pociredir
PRC2 inhibitor
|
Pociredir (FTX-6058) is an oral, allosteric polycomb repressive complex 2 (PRC2) inhibitor. |