| Cat. No. |
Product Name |
Information |
| PC-45092 |
MI-503
Menin-MLL inhibitor
|
MI-503 (MI 503) is a highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM. |
| PC-42907 |
3-Deazaneplanocin A hydrochloride
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) hydrochloride is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42587 |
3-Deazaneplanocin A
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42923 |
MM-102 trifluoroacetate
MLL1/WDR5 inhibitor
|
MM-102 trifluoroacetate is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-42922 |
MM-102
MLL1/WDR5 inhibitor
|
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-45489 |
PFI-2 hydrochloride
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-45488 |
PFI-2
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-26595 |
SCR-6920
PRMT5 inhibitor
|
SCR-6920 is a potent and selective, oral PRMT5 inhibitor with IC50 of 1.48 nM. |
| PC-26591 |
NSUN2 inhibitor AK
NSUN2 inhibitor
|
NSUN2 inhibitor AK (AK-968/36977265) is a small molecule inhibitor of RNA methyltransferase NSUN2, decreases m5C occupancy and GATM mRNA levels, shows anti-fibrotic efficacy. |
| PC-26589 |
UNC7242
PHF1/PHF19 inhibitor
|
UNC7242 is a small molecule antagonist of PRC2 components PHF1 and PHF19 with ITC Kd of 1.13 uM and 0.64 uM, displaces recombinant or endogenous PHF1 or 19 from nucleosomes. |
| PC-26565 |
GD433
NTMT1 inhibitor
|
GD433 is a potent, selective and substrate competitive inhibitor of N-terminal methyltransferase 1 (NTMT1) with IC50 of 27 nM. |
| PC-26542 |
EP102
METTL3 inhibitor
|
EP102 is a potent, selective METTL3 inhibitor with IC50 of 2 nM in SPA primary assay. |
