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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-AZD3470
AZD3470

Chemical Structure : AZD3470

CAS No.: 2918814-97-6

AZD3470 (AZD-3470)

货号: PC-26788Not For Human Use, Lab Use Only.

AZD3470 (AZD-3470) is a potent, seleective MTA-cooperative PRMT5 inhibitor, targets MTAP deficient advanced/metastatic cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AZD3470 (AZD-3470) is a potent, seleective MTA-cooperative PRMT5 inhibitor, targets MTAP deficient advanced/metastatic cancer cells.

    物理化学性质&存储条件

    分子量 435.43
    分子式 C23H19F2N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-((5-amino-6-fluoro-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)-1'-(but-2-yn-1-yl)-5-fluorospiro[isoindoline-1,3'-pyrrolidine]-2',3-dione

    参考文献

    1. Jelena Urosevic, et al. Cancer Res (2026) 86 (7_Supplement): 4489.

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