Heterochromatin protein 1 inhibitor (R)-18

Chemical Structure : Heterochromatin protein 1 inhibitor (R)-18

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货号: PC-25711Not For Human Use, Lab Use Only.

Heterochromatin protein 1 inhibitor (R)-18 is a small-molecule inhibitor of heterochromatin protein 1 (HP1), inhibits the HP1/H3K9me3 interaction with IC50 of 18.1 uM.

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生物&药学活性

Heterochromatin protein 1 inhibitor (R)-18 is a small-molecule inhibitor of heterochromatin protein 1 (HP1), inhibits the HP1/H3K9me3 interaction with IC50 of 18.1 uM.

物理化学性质&存储条件

分子量	340.38
分子式	C19H20N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-(4-nitrobenzyl)pyrrolidine

参考文献

1. Tokuyama A, et al. Bioorg Med Chem Lett. 2025 Nov 9:130469.